Trastuzumab rezetecan showed “clinically meaningful activity” in patients who had received previous treatment for HER2-mutated non–small cell lung cancer (NSCLC), according to recent findings from the phase 2 HORIZON-Lung trial. Ziming Li, MD, of the Shanghai Lung Cancer Center, the Shanghai Chest Hospital, and Shanghai Jiao Tong University School of Medicine, and colleagues conducted the study and published their findings in The Lancet Oncology. ...
Advertisement
Mara B. Antonoff, MD, FACS, discusses the organization's mission, the resources it offers, and her hopes for the future.
Learn how researchers determined the best treatment strategy for smoking cessation among patients who currently smoke.
The majority of symptoms at baseline consisted of pain, dyspnea, and fatigue.
The study investigators concluded that ivonescimab “might represent another treatment option in the first-line setting."
Dr. Liu unpacks key questions in the field, and the research that could address them.
Certain surgical procedures and margins were more frequent in patients who had suture-line recurrences.
The long-term follow-up data shows that PFS remains unreached in the subgroup of Asian patients in the CROWN study.
Researchers evaluated if there was a link between pretreatment systemic immune inflammation index levels and outcomes.
Study investigators say the combination "showed promising efficacy" in patients with relapsed small cell lung cancer.
Clinicians hypothesize that the genetic mutation, known as RUFY1-RET fusion, caused resistance to lorlatinib.